IMMUNOEXPRESSION OF PD-L1, CD4+ AND CD8+ CELL INFILTRATES AND TUMOR-INFILTRATING LYMPHOCYTES (TILS) IN THE MICROENVIRONMENT OF ACTINIC CHEILITIS AND LOWER LIP SQUAMOUS CELL CARCINOMA

Abstract Lower lip ACN squamous cell carcinomas (LLSCC) could be associated with a previous history of potentially malignant oral diseases (PMOD), especially actinic cheilitis (AC), with high sun exposure being a well-described risk factor.Immune evasion mechanisms, such as the PD-1/PD-L1 (programmed cell death protein 1/programmed death-ligand 1)

Abstract Paratuberculosis has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of paratuberculosis to be listed, Article 9 for the categorisation of paratuberculosis according to disease prevention and control rules Wrestling as i

One of the most significant causes of health problems worldwide is heavy metal contamination of vegetables.Hence, the study aimed to evaluate the concentration of ten heavy metals in commonly consumed vegetables and determine the health implications of their consumption.The vegetables studied included waterleaf (Talinum triangulare), fluted pumpkin

Abstract Background The glycosphingolipid sulfatide has previously been found in several mammalian tissues, but information on the uptake of Chopsticks exogenously administered sulfatide in different organs in vivo is limited.In pancreatic beta cells, sulfatide has been shown to be involved in insulin processing and secretion in vitro.In this study